Changes in superoxide radical and lipid peroxide formation in the brain, heart and liver during the lifetime of the rat

The free radical theory of aging was examined by measuring the formation of superoxide radical (SOR) and the level of lipid peroxides in various tissues of the aging rat. A significant increase in SOR production was seen in mitochondria prepared from the brain and the heart as rats aged. An elevatio...

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Veröffentlicht in:	Mechanisms of ageing and development 1987-11, Vol.41 (1), p.125-137
Hauptverfasser:	Sawada, Masaaki, Carlson, John C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing, cell death Aging - metabolism Animals Biological and medical sciences Brain - metabolism Brain, heart and liver mitochondria Cell physiology Electron Spin Resonance Spectroscopy Free Radicals Fundamental and applied biological sciences. Psychology Lipid peroxidation Lipid Peroxides - metabolism Liver - metabolism Male Mitochondria - metabolism Molecular and cellular biology Myocardium - metabolism Rats Rats, Inbred Strains Superoxide radical Superoxides - metabolism Vitamin E
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