Multiple proteins bind the insulin response element in the human IGFBP-1 promoter

An insulin response element (IRE) has been identified ∼100 base pairs (bp) 5′ to the transcription start site of the human insulin-like growth factor binding protein-1 (hIGFBP-1) gene. This cis element appears crucial to the multihormonal regulation of hIGFBP-1 expression in liver, since (i) an inta...

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Veröffentlicht in:	Progress in growth factor research 1995, Vol.6 (2), p.93-101
Hauptverfasser:	Powell, David R., Allander, Susanne V., Scheimann, Ann O., Wasserman, Richard M., Durham, Susan K., Suwanichkul, Adisak
Format:	Artikel
Sprache:	eng
Schlagworte:	DBP Deoxyribonuclease I - metabolism DNA - metabolism DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Hepatocyte Nuclear Factor 3-beta High Mobility Group Proteins - metabolism HMGA1a Protein HMGI HNF3 Humans IGFBP-1 Insulin-Like Growth Factor Binding Protein 1 - genetics IRE Leucine Zippers liver Nuclear Proteins - metabolism Promoter Regions, Genetic Transcription Factors - genetics Transcription Factors - metabolism
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