Association between angiotensin-converting-enzyme gene polymorphism and failure of renoprotective therapy

Summary Background Polymorphism in the gene for angiotensin-converting enzyme (ACE), especially the DD genotype, is associated with risk for cardiovascular disease. Glomerulosclerosis has similarities to atherosclerosis, and we looked at ACE gene polymorphism in patients with kidney disease who were...

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Veröffentlicht in:	The Lancet (British edition) 1996-01, Vol.347 (8994), p.94-95
Hauptverfasser:	van Essen, G.G, Rensma, P.L, de Zeeuw, D, Sluiter, W.J, Apperloo, A.J, de Jong, P.E, Scheffer, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - therapeutic use Angiotensin-Converting Enzyme Inhibitors - therapeutic use Antihypertensive agents Atenolol - therapeutic use Biological and medical sciences Blood pressure Cardiovascular diseases Cardiovascular system Clinical trials Double-Blind Method Drug therapy Enalapril - therapeutic use Enzymes Female Genes Genotype Glomerular Filtration Rate - drug effects Health risks Humans Kidney Diseases - prevention & control Kidneys Male Medical disorders Medical research Medical sciences Middle Aged Peptidyl-Dipeptidase A - genetics Pharmacology. Drug treatments Polymorphism, Genetic Renal function
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