Metabolism of Pyrilamine Maleate in Fischer 344 Rats, Part I: Activity Excretion Profiles

Male and female Fisher 344 rats (12 per group) were dosed by gavage with either 2 or 10 mg (based on the free amine) pyrilamine maleate containing about 12 and 6 µCi 14C-pyrilamine maleate, respectively, to determine excretion of the activity as a function of dose and sex with time. Urine and feces...

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Veröffentlicht in:	Journal of analytical toxicology 1987-11, Vol.11 (6), p.252-256
Hauptverfasser:	Thompson, Harold C., Holder, Claude L., Siitonen, Paul H., Rowland, Kenneth L., Gosnell, Aubrey B., Cmarik, Joan L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminopyridines - metabolism Animals Chromatography, Gas Chromatography, High Pressure Liquid Chromatography, Thin Layer Feces - analysis Female Male Pyrilamine - metabolism Pyrilamine - urine Rats Rats, Inbred F344
Online-Zugang:	Volltext
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