Pharmacokinetics of Cefixime After Once-a-Day and Twice-a-Day Dosing to Steady State

The pharmacokinetics of cefixime (CL 284,635; FK027), a new orally active broad‐spectrum cephalosporin, were determined in 26 healthy volunteers, after multiple 200‐mg twice‐a‐day (group 1; N = 13) or 400‐mg once‐a‐day (group 2; N = 13) dosing for 15 days. On study days 1, 8, and 15, mean peak serum...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of clinical pharmacology 1987-10, Vol.27 (10), p.807-812
Hauptverfasser:	Faulkner, Robert D., Bohaychuk, Wendy, Desjardins, Robert E., Look, Zee M., Haynes, John D., Weiss, Arnold I., Silber, B. Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Cefixime Cefotaxime - administration & dosage Cefotaxime - analogs & derivatives Cefotaxime - pharmacokinetics Chromatography, High Pressure Liquid Drug Administration Schedule Humans Male Medical sciences Pharmacology. Drug treatments
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!