Antimalarial properties of soy-bean fat emulsions

Intralipid ® and Ivelip ® are commercial preparations of soy-bean lipid extracts used for intravenous supplementation of lipids in various clinical conditions. They were found to inhibit the growth of Plasmodium falciparum in culture with an IC 50 of 8.07 ± 2.13 and 13.32 ± 2.05 mg.ml −1, respective...

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Veröffentlicht in:	International journal for parasitology 1995-12, Vol.25 (12), p.1457-1462
Hauptverfasser:	Deharo, E., Krugliak, M., Baccam, D., Ginsburg, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials - administration & dosage Antimalarials - pharmacology Antiparasitic agents Biological and medical sciences Chloroquine - administration & dosage drug Fat Emulsions, Intravenous - administration & dosage Fat Emulsions, Intravenous - pharmacology Female Glycine max Humans malaria Malaria - drug therapy Malaria - parasitology Medical sciences Mice Nucleic Acids - biosynthesis Oxidative Stress P. berghei P. vinckei petteri P. yoelii nigeriensis Pharmacology. Drug treatments Plasmodium Plasmodium - drug effects Plasmodium - growth & development Plasmodium - metabolism Plasmodium berghei - drug effects Plasmodium falciparum Plasmodium falciparum - drug effects Plasmodium yoelii - drug effects soy-bean fat emulsion
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