Isolation and quantification of Quillaja saponaria Molina saponins and lipids in iscom-matrix and iscoms

In the iscom, multiple copies of antigen are attached by hydrophobic interaction to a matrix which is built up by Quillaja triterpenoid saponins and lipids. Thus, the iscom presents antigen in multimeric form in a small particle with a built-in adjuvant resulting in a highly immunogenic antigen form...

Ausführliche Beschreibung