Stepwise activation of T cells. Role of the calcium ionophore A23187

The calcium ionophore A23187, at a concentration of 1 microgram/ml, is able to stimulate proliferation of freshly isolated peripheral blood lymphocytes, CD4+-enriched cells, or CD8+-enriched cells as measured by [3H]thymidine incorporation. This proliferation is accompanied by an increase in interle...

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Veröffentlicht in:	The Journal of immunology (1950) 1987-12, Vol.139 (12), p.3930-3934
Hauptverfasser:	Geller, RL, Gromo, G, Inverardi, L, Ferrero, E, Bach, FH
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - immunology Antigens, Surface - analysis Applied sciences Calcimycin - pharmacology Calcium - physiology Cell Division - drug effects Cells, Cultured Cytotoxicity, Immunologic - drug effects Exact sciences and technology Humans Interleukin-2 - biosynthesis Lymphocyte Activation - drug effects Other techniques and industries Receptors, Immunologic - analysis Receptors, Interleukin-2 T-Lymphocytes - drug effects T-Lymphocytes - immunology Tumor Necrosis Factor Receptor Superfamily, Member 7
Online-Zugang:	Volltext
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