Interleukin-1β induces the expression of HSP70, heme oxygenase and Mn-SOD in FACS-purified rat islet β-cells, but not in α-cells

The cytokine IL-1β has previously been demonstrated to induce the expression of the stress genes iNOS, hsp70, heme oxygenase and Mn-SOD in rat pancreatic islets in vitro. The aim of this study was to determine whether the IL-1β-induced effects are specific for the insulin producing β-cell, or whethe...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Immunology letters 1995-12, Vol.48 (2), p.145-148
Hauptverfasser:	Strandell, Eva, Buschard, Karsten, Saldeen, Johan, Welsh, Nils
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Separation Enzyme Induction - immunology Flow Cytometry Heme Oxygenase (Decyclizing) - biosynthesis Heme Oxygenase (Decyclizing) - drug effects Hsp70 HSP70 Heat-Shock Proteins - biosynthesis HSP70 Heat-Shock Proteins - drug effects Immunoblotting Insulin-producing cells Interleukin-1 Interleukin-1 - pharmacology Islets of Langerhans - cytology Islets of Langerhans - drug effects Islets of Langerhans - enzymology Male Mn-SOD Nitric oxide Rats Rats, Inbred Lew Superoxide Dismutase - biosynthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!