Serotonergic and cholinergic stimulation of inositol phosphate formation in the rabbit retina. Evidence for the presence of serotonin and muscarinic receptors

A direct assay which involves prelabelling with [ 3H]inositol has been performed to characterize receptor-mediated breakdown of inositol phospholipids in the rabbit retina. In the presence of 10 mM lithium, the receptor agonists, carbachol and serotonin (5-HT), evoked an increase in the accumulation...

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Veröffentlicht in:	Brain research 1987-09, Vol.421 (1), p.95-104
Hauptverfasser:	Cutcliffe, Nora, Osborne, Neville N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Atropine - pharmacology Biological and medical sciences Carbachol - pharmacology Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology In Vitro Techniques Inositol phosphate metabolism Inositol Phosphates - metabolism Muscarinic Norepinephrine - pharmacology Rabbits Receptor Receptors, Muscarinic - drug effects Receptors, Muscarinic - metabolism Receptors, Serotonin - drug effects Receptors, Serotonin - metabolism Retina Retina - drug effects Retina - metabolism Serotonergic Serotonin - pharmacology Serotonin - physiology Sugar Phosphates - metabolism Vertebrates: nervous system and sense organs
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