Preparation and characterization of monoclonal antibodies against the fifth component of rabbit complement (C5)

By immunizing mice genetically deficient in C5 we were able to obtain a group of monoclonal antibodies to rabbit C5 that cross-react with C5 from a wide variety of mammalian sera, including mouse. The specificity of the monoclonal antibodies was against native C5 and C5b but not C5a. The antibodies...

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Veröffentlicht in:	Journal of immunological methods 1987-12, Vol.105 (2), p.201-209
Hauptverfasser:	Giclas, P.C., Baker, S.L., Gillespie, M.L., Wilcox, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Applied sciences Biological Assay Chemical Precipitation Complement C5 - immunology Complement C5a Complement C5b Complement, rabbit Cross Reactions Exact sciences and technology Molecular Weight Monoclonal antibody Other techniques and industries Rabbits
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