Intrastriatal injection of opioid receptor agonists inhibits apomorphine-induced behavior in 6-hydroxydopamine-treated mice

The effects of intrastriatal (i.st.) injections of μ-, δ- and κ-selective opioid receptor agonists on the augmentation of apomorphine-induced behaviors were determined in 6-hydroxydopamine-treated mice by using multidimensional behavioral analyses. 6-Hydroxydopamine (16 μg/μl, i.st.) was unilaterall...

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Veröffentlicht in:	European journal of pharmacology 1995-12, Vol.294 (2), p.637-643
Hauptverfasser:	Toyoshi, Tohru, Ukai, Makoto, Kameyama, Tsutomu
Format:	Artikel
Sprache:	eng
Schlagworte:	6-Hydroxydopamine Animals Apomorphine Apomorphine - pharmacology Behavior, Animal - drug effects Biological and medical sciences Corpus Striatum - drug effects DAMGO ([ d-Ala 2, N-Me-Phe 4,Gly 5-ol]enkephalin) Dopamine - physiology DPLPE ([ d-Pen 2, l-Pen 5]enkephalin) Dynorphin A-(1–13) Dynorphins - pharmacology Enkephalin, Ala-MePhe-Gly Enkephalin, D-Penicillamine (2,5) Enkephalins - pharmacology Male Medical sciences Mice Mouse Naltrexone - analogs & derivatives Naltrexone - pharmacology Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Oxidopamine Peptide Fragments - pharmacology Peptidergic system (neuropeptide, opioid peptide, opiates...). Adenosinergic and purinergic systems Pharmacology. Drug treatments Receptors, Opioid - agonists
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