Comparative Effects of Procainamide and Its N-Acetylated Metabolite in Conscious Dogs with Atrioventricular Block: Plasma Concentration—Response Relationships

SUMMARYThe effects of procainamide and its metabolite N-acetylprocainamide (NAPA) on atrial effective refractory period (AERP). atrial rate, ventricular rate, and mean blood pressure were investigated in conscious dogs with chronic atrioventricular block and implanted atrial pacing electrodes. Proca...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1987-11, Vol.10 (5), p.562-567
Hauptverfasser:	Boucher, M, Dubray, C, Paire, M, Duchene-Marullaz, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Acecainide - blood Acecainide - pharmacology Animals Blood Pressure - drug effects Cardiac Pacing, Artificial Dogs Dose-Response Relationship, Drug Female Heart Block - physiopathology Heart Rate - drug effects Male Procainamide - analogs & derivatives Procainamide - blood Procainamide - pharmacology
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