Protection from HIV-1 envelope-bearing chimeric simian immunodeficiency virus (SHIV) in rhesus macaques infected with attenuated SIV : consequences of challenge

To determine whether prior infection with simian immunodeficiency virus (SIV)BK28 protects macaques from subsequent exposure to an HIV-1 envelope chimeric SIV (SHIV). Also, to determine the consequences of viral challenge on CD4 numbers and virus load on the current SIV infection. A total of 12 matu...

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Veröffentlicht in:	AIDS (London) 1995-12, Vol.9 (12), p.F13-F18
Hauptverfasser:	BOGERS, W. M. J. M, NIPHUIS, H, TEN HAAFT, P, LAMAN, J. D, KOORNSTRA, W, HEENEY, J. L
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Amino Acid Sequence Animals Biological and medical sciences CD4 Lymphocyte Count Chimera DNA, Viral - analysis Flow Cytometry Gene Products, env - genetics Gene Products, env - immunology HIV-1 - genetics HIV-1 - immunology human immunodeficiency virus 1 Human viral diseases Infectious diseases Lentivirus Infections - prevention & control Macaca mulatta Medical sciences Molecular Sequence Data Polymerase Chain Reaction simian immunodeficiency virus Simian Immunodeficiency Virus - genetics Simian Immunodeficiency Virus - immunology Vaccines, Attenuated - therapeutic use Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Vaccines - therapeutic use Virus Cultivation
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