Nabumetone pharmacokinetics in patients with varying degrees of renal impairment

The pharmacokinetics of 1 g of oral nabumetone were studied in 20 patients divided into three groups according to the creatinine clearance rate of each. Pharmacokinetic assessment was made on the presence of the major and active metabolite found in the plasma, 6-methoxy-2-naphthylacetic acid, BRL 10...

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Veröffentlicht in:	The American journal of medicine 1987-10, Vol.83 (4), p.107-109
Hauptverfasser:	Boelaert, Johan R., Jonnaert, Hans A., Daneels, Roger F., Schurgers, Mario L., Thawley, Alan R., Undre, Nasrullah A., Cooper, Denis L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics Butanones - pharmacokinetics Female Humans Kidney Diseases - metabolism Male Middle Aged Nabumetone Naphthaleneacetic Acids - pharmacokinetics
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