The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system

It has been proposed that disruption of cholinergic input to the hippocampus and cortex contributes to the learning and memory deficits associated with aging. The data reviewed here, however, suggest that the oft-stated generalization that normal aging is characterized by disruption of cholinergic i...

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Veröffentlicht in:	Brain Research Reviews 1987-11, Vol.12 (4), p.423-438
1. Verfasser:	Decker, Michael W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Acetylcholinesterase - metabolism Aging Aging - metabolism Aging - physiology Anatomy Animals Biological and medical sciences Cell Count Central nervous system Cerebral cortex Choline O-Acetyltransferase - metabolism Cholinergic Fibers - metabolism Cholinergic Fibers - physiology Female Frontal Lobe - cytology Frontal Lobe - growth & development Frontal Lobe - metabolism Fundamental and applied biological sciences. Psychology Hippocampus Hippocampus - cytology Hippocampus - growth & development Hippocampus - metabolism Male Mice Rats Vertebrates: nervous system and sense organs
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