Isolation of Mutants of Candida Glabrata Resistant to Miconazole

Elucidation of the mode of action of azole antifungals would be aided by studying resistant mutants. It is difficult to obtain mutants of Candida albicans in the laboratory, and there have only been a few studies on clinical isolates which seem to be resistant because of impaired drug uptake. C. gla...

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Veröffentlicht in:	CRC critical reviews in microbiology 1987, Vol.15 (1), p.103-110
Hauptverfasser:	Nicholas, Richard O., Burton, Jacqueline A., Kerridge, David, Wayman, Frances J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - metabolism Biological Transport Candida - drug effects Candida - genetics Candida - isolation & purification Drug Resistance, Microbial Miconazole - metabolism Miconazole - pharmacology Mutation Oxygen Consumption - drug effects Spheroplasts - drug effects Spheroplasts - metabolism
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