Ischemic stroke associated with anticardiolipin antibodies
Anticardiolipin antibodies are a group of antiphospholipid autoantibodies seen primarily in patients with systemic lupus erythematosus and other autoimmune diseases. We report 3 patients, 2 without systemic lupus, who suffered ischemic brain infarction associated with these antibodies in the absence...
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Veröffentlicht in: | Stroke (1970) 1987-11, Vol.18 (6), p.1101-1106 |
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container_title | Stroke (1970) |
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creator | LEVINE, S. R KIM, S DEEGAN, M. J WELCH, K. M. A |
description | Anticardiolipin antibodies are a group of antiphospholipid autoantibodies seen primarily in patients with systemic lupus erythematosus and other autoimmune diseases. We report 3 patients, 2 without systemic lupus, who suffered ischemic brain infarction associated with these antibodies in the absence of detectable lupus anticoagulant activity. Anticardiolipin antibodies, possibly associated with a lupus anticoagulant-like thrombotic tendency, may be a newly recognized cause of ischemic stroke. |
doi_str_mv | 10.1161/01.STR.18.6.1101 |
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R ; KIM, S ; DEEGAN, M. J ; WELCH, K. M. A</creator><creatorcontrib>LEVINE, S. R ; KIM, S ; DEEGAN, M. J ; WELCH, K. M. A</creatorcontrib><description>Anticardiolipin antibodies are a group of antiphospholipid autoantibodies seen primarily in patients with systemic lupus erythematosus and other autoimmune diseases. We report 3 patients, 2 without systemic lupus, who suffered ischemic brain infarction associated with these antibodies in the absence of detectable lupus anticoagulant activity. Anticardiolipin antibodies, possibly associated with a lupus anticoagulant-like thrombotic tendency, may be a newly recognized cause of ischemic stroke.</description><identifier>ISSN: 0039-2499</identifier><identifier>EISSN: 1524-4628</identifier><identifier>DOI: 10.1161/01.STR.18.6.1101</identifier><identifier>PMID: 3120359</identifier><identifier>CODEN: SJCCA7</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adult ; Autoantibodies - analysis ; Biological and medical sciences ; Blood Coagulation Factors - analysis ; Blood Coagulation Factors - immunology ; Brain Ischemia - diagnostic imaging ; Brain Ischemia - immunology ; Cardiolipins - immunology ; Cerebral Infarction - diagnostic imaging ; Cerebral Infarction - immunology ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Lupus Coagulation Inhibitor ; Lupus Erythematosus, Systemic - immunology ; Male ; Medical sciences ; Middle Aged ; Neurology ; Tomography, X-Ray Computed ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>Stroke (1970), 1987-11, Vol.18 (6), p.1101-1106</ispartof><rights>1988 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c401t-891c6fd9ebf3ee7fc551efc760605c04b727d431ce9f4eb8c2fbf0f005a49af13</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,3688,27929,27930</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7541633$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3120359$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LEVINE, S. R</creatorcontrib><creatorcontrib>KIM, S</creatorcontrib><creatorcontrib>DEEGAN, M. J</creatorcontrib><creatorcontrib>WELCH, K. M. A</creatorcontrib><title>Ischemic stroke associated with anticardiolipin antibodies</title><title>Stroke (1970)</title><addtitle>Stroke</addtitle><description>Anticardiolipin antibodies are a group of antiphospholipid autoantibodies seen primarily in patients with systemic lupus erythematosus and other autoimmune diseases. We report 3 patients, 2 without systemic lupus, who suffered ischemic brain infarction associated with these antibodies in the absence of detectable lupus anticoagulant activity. Anticardiolipin antibodies, possibly associated with a lupus anticoagulant-like thrombotic tendency, may be a newly recognized cause of ischemic stroke.</description><subject>Adult</subject><subject>Autoantibodies - analysis</subject><subject>Biological and medical sciences</subject><subject>Blood Coagulation Factors - analysis</subject><subject>Blood Coagulation Factors - immunology</subject><subject>Brain Ischemia - diagnostic imaging</subject><subject>Brain Ischemia - immunology</subject><subject>Cardiolipins - immunology</subject><subject>Cerebral Infarction - diagnostic imaging</subject><subject>Cerebral Infarction - immunology</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Female</subject><subject>Humans</subject><subject>Lupus Coagulation Inhibitor</subject><subject>Lupus Erythematosus, Systemic - immunology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Tomography, X-Ray Computed</subject><subject>Vascular diseases and vascular malformations of the nervous system</subject><issn>0039-2499</issn><issn>1524-4628</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLAzEUhYMotVb3boRZiLsZ781jZuJOio9CQdC6DplMQqPzqMkU8d872tLV5dzzWHyEXCJkiDneAmZvq9cMyywfH4BHZIqC8pTntDwmUwAmU8qlPCVnMX4AAGWlmJAJQwpMyCm5W0Sztq03SRxC_2kTHWNvvB5snXz7YZ3obvBGh9r3jd_47l9Xfe1tPCcnTjfRXuzvjLw_Pqzmz-ny5Wkxv1-mhgMOaSnR5K6WtnLM2sIZIdA6U-SQgzDAq4IWNWdorHTcVqWhrnLgAITmUjtkM3Kz292E_mtr46BaH41tGt3ZfhtVUZScckHHIOyCJvQxBuvUJvhWhx-FoP5wKUA14lJYqlz94RorV_vtbdXa-lDY8xn9672vo9GNC7ozPh5iheCYM8Z-AUczczo</recordid><startdate>19871101</startdate><enddate>19871101</enddate><creator>LEVINE, S. R</creator><creator>KIM, S</creator><creator>DEEGAN, M. J</creator><creator>WELCH, K. M. A</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19871101</creationdate><title>Ischemic stroke associated with anticardiolipin antibodies</title><author>LEVINE, S. R ; KIM, S ; DEEGAN, M. J ; WELCH, K. M. A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c401t-891c6fd9ebf3ee7fc551efc760605c04b727d431ce9f4eb8c2fbf0f005a49af13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Adult</topic><topic>Autoantibodies - analysis</topic><topic>Biological and medical sciences</topic><topic>Blood Coagulation Factors - analysis</topic><topic>Blood Coagulation Factors - immunology</topic><topic>Brain Ischemia - diagnostic imaging</topic><topic>Brain Ischemia - immunology</topic><topic>Cardiolipins - immunology</topic><topic>Cerebral Infarction - diagnostic imaging</topic><topic>Cerebral Infarction - immunology</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Female</topic><topic>Humans</topic><topic>Lupus Coagulation Inhibitor</topic><topic>Lupus Erythematosus, Systemic - immunology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Tomography, X-Ray Computed</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LEVINE, S. R</creatorcontrib><creatorcontrib>KIM, S</creatorcontrib><creatorcontrib>DEEGAN, M. J</creatorcontrib><creatorcontrib>WELCH, K. M. A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Stroke (1970)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LEVINE, S. R</au><au>KIM, S</au><au>DEEGAN, M. J</au><au>WELCH, K. M. A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ischemic stroke associated with anticardiolipin antibodies</atitle><jtitle>Stroke (1970)</jtitle><addtitle>Stroke</addtitle><date>1987-11-01</date><risdate>1987</risdate><volume>18</volume><issue>6</issue><spage>1101</spage><epage>1106</epage><pages>1101-1106</pages><issn>0039-2499</issn><eissn>1524-4628</eissn><coden>SJCCA7</coden><abstract>Anticardiolipin antibodies are a group of antiphospholipid autoantibodies seen primarily in patients with systemic lupus erythematosus and other autoimmune diseases. We report 3 patients, 2 without systemic lupus, who suffered ischemic brain infarction associated with these antibodies in the absence of detectable lupus anticoagulant activity. Anticardiolipin antibodies, possibly associated with a lupus anticoagulant-like thrombotic tendency, may be a newly recognized cause of ischemic stroke.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>3120359</pmid><doi>10.1161/01.STR.18.6.1101</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; American Heart Association Journals; Journals@Ovid Complete; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Adult Autoantibodies - analysis Biological and medical sciences Blood Coagulation Factors - analysis Blood Coagulation Factors - immunology Brain Ischemia - diagnostic imaging Brain Ischemia - immunology Cardiolipins - immunology Cerebral Infarction - diagnostic imaging Cerebral Infarction - immunology Enzyme-Linked Immunosorbent Assay Female Humans Lupus Coagulation Inhibitor Lupus Erythematosus, Systemic - immunology Male Medical sciences Middle Aged Neurology Tomography, X-Ray Computed Vascular diseases and vascular malformations of the nervous system |
title | Ischemic stroke associated with anticardiolipin antibodies |
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