Application of the fiber‐optic perfusion fluorometer to absorption and exsorption studies in hairless mouse skin

This study was undertaken to test the fiber‐optic perfusion fluorometer as a direct means of evaluating skin absorption and exsorption in hairless mice. Skin‐barrier compromise was accomplished in the absorption experiments by application of dimethyl sulfoxide to the skin surface or by partial remov...

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Veröffentlicht in:	The Anatomical record 1987-09, Vol.219 (1), p.102-107
Hauptverfasser:	Shackleford, John M., Yielding, K. Lemone
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Animals Biological and medical sciences Capsaicin - pharmacokinetics Dimethyl Sulfoxide - pharmacokinetics Evaluation Studies as Topic Fiber Optic Technology Fluorescein Fluoresceins Fluorometry - instrumentation Fundamental and applied biological sciences. Psychology Male Mice Mice, Hairless - metabolism Optical Fibers Perfusion Skin - metabolism Vertebrates: skin, associated glands, phaneres, light organs, various exocrine glands (salt gland, uropygial gland...), adipose tissue, connective tissue
Online-Zugang:	Volltext
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