Angiogenesis in malignant gliomas

One event that accompanies glioma progression is the upregulation of angiogenesis. Low‐grade gliomas are moderately vascularized tumors whereas high‐grade gliomas show prominent microvascular proliferations and areas of high vascular density. To analyze the molecular mechanisms underlying glioma ang...

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Veröffentlicht in:	Glia 1995-11, Vol.15 (3), p.339-347
Hauptverfasser:	Plate, Karl H., Risau, Werner
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain Neoplasms - blood supply Brain Neoplasms - genetics Brain Neoplasms - metabolism Brain Neoplasms - pathology Brain Neoplasms - therapy Endothelial Growth Factors - genetics Endothelial Growth Factors - metabolism Endothelium FGF Genes, Tumor Suppressor Genetic Therapy Glioma - blood supply Glioma - genetics Glioma - metabolism Glioma - pathology Glioma - therapy Glycoproteins - genetics Glycoproteins - metabolism Humans Medical sciences Neovascularization, Pathologic Neurology p53 Receptor Protein-Tyrosine Kinases - genetics Receptor Protein-Tyrosine Kinases - metabolism Receptors, Growth Factor - genetics Receptors, Growth Factor - metabolism Receptors, Vascular Endothelial Growth Factor Regional Blood Flow - physiology Tie-1 Tie-2 Tumor progression Tumors of the nervous system. Phacomatoses Vascular Endothelial Growth Factor A Vascularization VEGF VEGFR-1 VEGFR-2 VHL
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