Substrate selection in the isolated working rat heart : effects of reperfusion, afterload, and concentration

A study of substrate selection in the isolated heart was made using 13C NMR isotopomer analysis, a method that unequivocally identifies relative substrate utilization. This technique has several advantages over conventional approaches used to study this problem. It detects the labeling of metabolic...

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Veröffentlicht in:	Basic research in cardiology 1995-09, Vol.90 (5), p.388-396
Hauptverfasser:	JEFFREY, F. M. H, DICZKU, V, SHERRY, A. D, MALLOY, C. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetoacetates - pharmacokinetics Animals Biological and medical sciences Butyrates - pharmacokinetics Carbon Dioxide - metabolism Carbon Radioisotopes Cardiovascular system Fatty Acids - pharmacokinetics Heart - drug effects Heart - physiopathology Hemodynamics In Vitro Techniques Investigative techniques of hemodynamics Investigative techniques, diagnostic techniques (general aspects) Lactates - pharmacokinetics Lactic Acid Magnetic Resonance Spectroscopy Male Medical sciences Myocardial Reperfusion Myocardium - metabolism Rats Rats, Sprague-Dawley
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