Oral ciprofloxacin as prophylaxis in gastroduodenal surgery

One hundred and fifty patients undergoing gastroduodenal surgery were randomly allocated to receive intravenous (iv) cefuroxime, iv ciprofloxacin or oral ciprofloxacin as prophylaxis. There were no differences in the incidence of postoperative infection complications or duration of stay among the th...

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Veröffentlicht in:	The Journal of hospital infection 1995-07, Vol.30 (3), p.211-216
Hauptverfasser:	McArdle, C.S., Morran, C.G., Anderson, J.R., Pettit, L., Gemmell, C.G., Sleigh, J.D., Tillotson, G.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Anti-Infective Agents - administration & dosage Anti-Infective Agents - therapeutic use Antibacterial agents Antibiotic Prophylaxis Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial Infections - prevention & control Biological and medical sciences Cefuroxime - administration & dosage Cefuroxime - therapeutic use Ciprofloxacin Ciprofloxacin - administration & dosage Ciprofloxacin - therapeutic use Duodenum - surgery Female Humans Injections, Intravenous Length of Stay - statistics & numerical data Male Medical sciences Middle Aged Pharmacology. Drug treatments Scotland Stomach - surgery Surgical Wound Infection - prevention & control
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Beschreibung
Zusammenfassung:	One hundred and fifty patients undergoing gastroduodenal surgery were randomly allocated to receive intravenous (iv) cefuroxime, iv ciprofloxacin or oral ciprofloxacin as prophylaxis. There were no differences in the incidence of postoperative infection complications or duration of stay among the three groups. Oral ciprofloxacin offers obvious advantages in terms of ease of administration and cost.
ISSN:	0195-6701 1532-2939
DOI:	10.1016/S0195-6701(95)90316-X