The receptor-mediated action of sex steroid binding protein (SBP, SHBG): Accumulation of cAMP in MCF-7 cells under SBP and estradiol treatment

The interaction of sex steroid binding protein (SBP) with its specific receptor in MCF-7 cell (estrogen-sensitive human breast cancer cells), followed by the binding of estradiol (E 2) to the complex SBP-receptor, induced a significant accumulation of intracellular cAMP. SBP alone as well as E 2 alo...

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Veröffentlicht in:Steroids 1994-11, Vol.59 (11), p.661-667
Hauptverfasser: Fissore, Federica, Fortunati, Nicoletta, Comba, Alessandra, Fazzari, Annamaria, Gaidano, Gianpiero, Berta, Laura, Frairia, Roberto
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Sprache:eng
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