The mouse fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster

The gene for the mouse Fas ligand was cloned and its chromosomal position determined. Fasl was tightly linked to gld (no crossovers in 567 meiotic events) on mouse chromosome 1 and closely linked with a novel member of the same TNF family of ligands, the 0x40 ligand (0 x401,1 crossover in 567 meioti...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 1994-05, Vol.1 (2), p.131-136
Hauptverfasser:	Lynch, David H., Watson, Mark L., Alderson, Mark R., Baum, Peter R., Miller, Robert E., Tough, Teresa, Gibson, Marylou, Davis-Smith, Terri, Smiths, Craig A., Hunter, Kent, Bhat, Deepti, Din, Wenie, Goodwin, Raymond G., Seldin, Michael F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Autoimmune Diseases - genetics Base Sequence Cell Line Chromosome Mapping Cloning, Molecular DNA - genetics Fas Ligand Protein Genetic Linkage Membrane Glycoproteins - genetics Mice Mice, Inbred C3H Mice, Inbred C57BL Molecular Sequence Data Multigene Family Phenotype Point Mutation Transfection Tumor Necrosis Factor-alpha - genetics
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