Evaluation of tetracycline raw materials and finished products found on the Kenyan market
Contents of tetracycline, its degradation products (epitetracycline, epianhydrotetracycline, anhydrotetracycline) and a fermentation impurity (2-acetyl-2-decarboxamidotetracycline) were determined in four raw materials, 12 batches of six ointment products, four eye ointment products and nine batches...
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| Veröffentlicht in: | Journal of pharmaceutical and biomedical analysis 1994-12, Vol.12 (12), p.1483-1488 |
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| container_end_page | 1488 |
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| container_issue | 12 |
| container_start_page | 1483 |
| container_title | Journal of pharmaceutical and biomedical analysis |
| container_volume | 12 |
| creator | Muritu, John Waititu Kibwage, Isaac Ongubo Maitai, Charles Karimi Hoogmartens, Jos |
| description | Contents of tetracycline, its degradation products (epitetracycline, epianhydrotetracycline, anhydrotetracycline) and a fermentation impurity (2-acetyl-2-decarboxamidotetracycline) were determined in four raw materials, 12 batches of six ointment products, four eye ointment products and nine batches of five capsule products, all sampled from the Kenyan market. The analytical method was liquid chromatography on a column packed with a poly(styrenedivinylbenzene) material (8-μm PLRP-S 100 Å). All raw materials and finished products had tetracycline contents and impurity levels within the prescribed compendial limits. |
| doi_str_mv | 10.1016/0731-7085(94)00105-7 |
| format | Article |
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Drug treatments</subject><subject>raw materials</subject><subject>Tetracycline</subject><subject>Tetracycline - chemistry</subject><subject>Tetracycline - standards</subject><issn>0731-7085</issn><issn>1873-264X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1rVDEUhoModVr9BwpZSNHFrfnOZCNIaVVacKOgq5CbnNDondya5LbMvzfjDLN0deCc5z28PAi9ouSCEqreE83poMlavjXiHSGUyEE_QSu61nxgSvx4ilZH5Dk6rfUXIURSI07QiVZGcU1X6OfVg5sW19Kc8Rxxg1ac3_opZcDFPeKNa1CSmyp2OeCYcqp3EPB9mcPiW8VxXvq-h9sd4BvIW5d7pvyG9gI9iz0HLw_zDH2_vvp2-Xm4_frpy-XH28HztWoDMM5GFiUPnkk9yihDZApAs6AcZ37d98GPigrPmXEkGCrNqIwMTGhDDD9D5_u_vdOfBWqzm1Q9TJPLMC_Vaq2NEJx1UOxBX-ZaC0R7X1LvurWU2J1Ru9Nld7qsEfafUat77PXh_zJuIBxDB4X9_uZwd9W7KRaXfapHjHOluZAd-7DHoLt4SFBs9Qmyh5AK-GbDnP7f4y_85pJq</recordid><startdate>19941201</startdate><enddate>19941201</enddate><creator>Muritu, John Waititu</creator><creator>Kibwage, Isaac Ongubo</creator><creator>Maitai, Charles Karimi</creator><creator>Hoogmartens, Jos</creator><general>Elsevier B.V</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19941201</creationdate><title>Evaluation of tetracycline raw materials and finished products found on the Kenyan market</title><author>Muritu, John Waititu ; Kibwage, Isaac Ongubo ; Maitai, Charles Karimi ; Hoogmartens, Jos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-e232b2f53dc257b5f5df26ee72d6a32c8dc2dcb614c329a0d9159b695d2479093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Analysis</topic><topic>Biological and medical sciences</topic><topic>Capsules - standards</topic><topic>Chromatography, Liquid</topic><topic>finished products</topic><topic>General pharmacology</topic><topic>impurities</topic><topic>Kenya</topic><topic>Medical sciences</topic><topic>Ointments - standards</topic><topic>Pharmacology. 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| identifier | ISSN: 0731-7085 |
| ispartof | Journal of pharmaceutical and biomedical analysis, 1994-12, Vol.12 (12), p.1483-1488 |
| issn | 0731-7085 1873-264X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_77794432 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Analysis Biological and medical sciences Capsules - standards Chromatography, Liquid finished products General pharmacology impurities Kenya Medical sciences Ointments - standards Pharmacology. Drug treatments raw materials Tetracycline Tetracycline - chemistry Tetracycline - standards |
| title | Evaluation of tetracycline raw materials and finished products found on the Kenyan market |
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