Effector Functions of Antibody and CD8+Cells in Resolution of Rotavirus Infection and Protection against Reinfection in Mice

The importance of antibody and CD8+cells in resolution of murine rotavirus (EDIM) infection and protection against reinfection was examined with two strains of B-cell-deficient mice. Following inoculation of one strain (JHD), rotavirus infection was resolved within days, but when later reinoculated...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1995-12, Vol.214 (2), p.387-397
Hauptverfasser:	MCNEAL, MONICA M., BARONE, K.SIOBHAN, RAE, MARY N., WARD, RICHARD L.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals Antibodies, Viral - immunology CD8-Positive T-Lymphocytes - immunology Disease Models, Animal Feces - virology Female Gene Deletion Immunoglobulin Heavy Chains - genetics Immunoglobulin Heavy Chains - immunology Immunoglobulin mu-Chains - genetics Immunoglobulin mu-Chains - immunology Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Mutant Strains Rotavirus - immunology Rotavirus - isolation & purification Rotavirus Infections - immunology Rotavirus Infections - prevention & control Rotavirus Infections - virology Virus Shedding
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