Calcium supplementation for preterm and low birth-weight neonates

Early neonatal hypocalcemia is a common problem in prematurely born infants. To prevent it, therapy with intravenous calcium is often advised. We compared the efficacy and side-effects of intravenous and oral calcium supplementation in preterm and low birth-weight babies. Both the groups were comparable for birth weight, gestational age and cord blood calcium level. Oral calcium administration was as efficacious as intravenous administration in babies of all gestational age groups and birth-weight groups. Side effects associated with therapy were less common and of lesser severity in oral supplementation group. Lower cost and ease of administration were additional benefits.