p53 and PCNA Expression in Malignant Melanomas of the Head and Neck

Mutation in the p53 tumor suppressor gene is the most common genetic alteration in human cancer. As in mutant p53 the protein is stabilised and the half‐life is extended, it becomes detectable by immunohistological staining. p53 immunoreactivity thus seems to be a potential biomarker for the assessm...

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Veröffentlicht in:	Pigment cell research 1994-10, Vol.7 (5), p.354-357
Hauptverfasser:	GIROD, SABINE C., GROTH, W, JUNK, M., GERLACH, K.-L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal Cell Division Gene Expression Head and neck Head and Neck Neoplasms - chemistry Head and Neck Neoplasms - pathology Humans Immunohistochemistry Malignant melanoma Melanoma - chemistry Melanoma - pathology PCNA Proliferating Cell Nuclear Antigen - analysis Tumor suppressor genes Tumor Suppressor Protein p53 - analysis
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