Canyon Rim Residues, Including Antigenic Determinants, Modulate Serotype-Specific Binding of Polioviruses to Mutants of the Poliovirus Receptor

Several mouse cell lines expressing hybrid human poliovirus receptors (hPVRs) bearing mutations in the first immunoglobulin-like domain were previously characterized for their defective binding and replication of poliovirus type 1 Mahoney (G. Bernhardt, J. Harber, A. Zibert, M. DeCrombrugghe, and E....

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1995-12, Vol.214 (2), p.559-570
Hauptverfasser:	HARBER, JAMES, BERNHARDT, GÜNTER, LU, HUI-HUA, SGRO, JEAN-YVES, WIMMER, ECKARD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Capsid - genetics Capsid - metabolism Capsid - ultrastructure Cell Line Defective Viruses - metabolism DNA, Viral Epitopes - metabolism HeLa Cells Humans Mice Molecular Sequence Data Mutation Neutralization Tests poliovirus Poliovirus - isolation & purification Poliovirus - metabolism Poliovirus - physiology Receptors, Virus - genetics Receptors, Virus - metabolism Receptors, Virus - ultrastructure Serotyping Virus Replication
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