Drug mixture which improves survival of ischemic rabbit epigastric skin flaps

The chief aim of this study was to maximize flap survival by counteracting the pathophysiological changes occurring during ischemia‐reperfusion. Rabbit epigastric skin flaps given 21 hours of ischemia were infused intra‐arterially with selected drugs at the start of reperfusion. Compared with contro...

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Veröffentlicht in:	Microsurgery 1994, Vol.15 (10), p.685-692
Hauptverfasser:	Lepore, Diana A., Knight, Kenneth R., Bhattacharya, Surajit, Ritz, Morris, Robbins, Sonia P., Sieg, Peter, Morrison, Wayne A., O'Brien, Bernard McC
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - administration & dosage Animals Deferoxamine - administration & dosage Dextrans - administration & dosage Drug Combinations Epoprostenol - administration & dosage Heparin - administration & dosage Infusions, Intra-Arterial Nitrendipine - administration & dosage Rabbits Reperfusion Injury - drug therapy Streptokinase - administration & dosage Surgical Flaps Urokinase-Type Plasminogen Activator - administration & dosage Vasodilator Agents - therapeutic use
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