Stabilisation of neuromuscular junctions by leupeptin increases motor unit size in partially denervated rat muscles

The effect of inhibiting the calcium activated neutral protease (CAMP) by leupeptin on force output and motor unit size of the partially denervated rat EDL muscle was studied. Partial denervation was performed under anaesthesia by section of the L 4 ventral ramus in 3- and 18-day-old Wistar rats. Tw...

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Veröffentlicht in:	Brain research. Developmental brain research 1995-09, Vol.88 (2), p.186-193
Hauptverfasser:	Tyc, F, Vrbová, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calpain - antagonists & inhibitors Cell Size - drug effects EDL Leupeptin Leupeptins - pharmacology Motor Neurons - drug effects Motor unit Muscle Denervation Nerve Endings - drug effects Neuromuscular Junction - drug effects Partial denervation Rats Rats, Wistar
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