High risk HLA-DR/DQ genotypes for IDD confer susceptibility to autoantibodies but DQB10602 does not prevent them

Although HLA class II genes are important in insulin-dependent diabetes (IDD), their influence on the expression of IDD-associated autoantibodies (aAb) is unclear. We compared HLA-DRB1 and DQB1 gene frequencies in several Caucasian groups: 191 normal controls, 378 IDD patients, and 357 non-diabetic...

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