Dendritic Ca2+ accumulations and metabotropic glutamate receptor activation associated with an n-methyl-d-aspartate receptor-independent long-term potentiation in hippocampal CA1 neurons

Bathing hippocampal slices in the potassium channel blocker tetraethylammonium (TEA), while stimulating the Schafer collaterals at a low frequency, induces Ca2+ ‐dependent, N‐methyl‐D‐aspartate (NMDA) receptor‐independent long‐term potentiation of synaptic transmission (LTPk) in CA1 neurons. We have...

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Veröffentlicht in:	Hippocampus 1994-10, Vol.4 (5), p.546-558
Hauptverfasser:	Petrozzino, Jeffrey J., Connor, John A.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Amino-5-phosphonovalerate - pharmacology Action Potentials Animals calcium Calcium - metabolism Dendrites - metabolism Dizocilpine Maleate - pharmacology fura-2 guinea pig Guinea Pigs Hippocampus - cytology Hippocampus - drug effects Hippocampus - metabolism imaging Long-Term Potentiation mag-fura-5 Neurons - drug effects Neurons - metabolism Nimodipine - pharmacology Potassium Channels - drug effects Protein Kinase C - antagonists & inhibitors Protein Kinase C - metabolism Receptors, Metabotropic Glutamate - agonists Receptors, Metabotropic Glutamate - antagonists & inhibitors Receptors, Metabotropic Glutamate - metabolism Receptors, N-Methyl-D-Aspartate - physiology Tetraethylammonium Tetraethylammonium Compounds - pharmacology
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