Modified Levinson's test in rapid diagnosis of tuberculous meningitis
Modified Levinson's precipitation test was done in 64 cases of TBM, 54 cases of TBM with inconsistent CSF finding, and 32 cases of pyogenic meningitis. The test was positive in 93.7% cases of TBM (sensitivity, 93.7%), 85.5% cases of TBM with doubtful diagnosis and in 9.4% cases of pyogenic meni...
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Veröffentlicht in: | Indian pediatrics 1994-03, Vol.31 (3), p.301-304 |
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creator | VEENA GUPTA AGARWAL, V. K MATHUR, S TRIPATHI, V. N ASHA AGARWAL MAYA BHALLA KHADWEL, A |
description | Modified Levinson's precipitation test was done in 64 cases of TBM, 54 cases of TBM with inconsistent CSF finding, and 32 cases of pyogenic meningitis. The test was positive in 93.7% cases of TBM (sensitivity, 93.7%), 85.5% cases of TBM with doubtful diagnosis and in 9.4% cases of pyogenic meningitis (specificity 90.6%) compared to 79.7%, 72.2% and 18.8% in original Levinson's test, respectively. With CSF examination only 66% cases of TBM could be diagnosed while with modified Levinson's test and CSF analysis 89% cases could be diagnosed (p < 0.001). So modified Levinson's test for diagnosis of TBM is better than Levinson's test (p < 0.05) with an added advantage of time saving. |
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K ; MATHUR, S ; TRIPATHI, V. N ; ASHA AGARWAL ; MAYA BHALLA ; KHADWEL, A</creator><creatorcontrib>VEENA GUPTA ; AGARWAL, V. K ; MATHUR, S ; TRIPATHI, V. N ; ASHA AGARWAL ; MAYA BHALLA ; KHADWEL, A</creatorcontrib><description>Modified Levinson's precipitation test was done in 64 cases of TBM, 54 cases of TBM with inconsistent CSF finding, and 32 cases of pyogenic meningitis. The test was positive in 93.7% cases of TBM (sensitivity, 93.7%), 85.5% cases of TBM with doubtful diagnosis and in 9.4% cases of pyogenic meningitis (specificity 90.6%) compared to 79.7%, 72.2% and 18.8% in original Levinson's test, respectively. With CSF examination only 66% cases of TBM could be diagnosed while with modified Levinson's test and CSF analysis 89% cases could be diagnosed (p < 0.001). So modified Levinson's test for diagnosis of TBM is better than Levinson's test (p < 0.05) with an added advantage of time saving.</description><identifier>ISSN: 0019-6061</identifier><identifier>EISSN: 0974-7559</identifier><identifier>PMID: 7896365</identifier><identifier>CODEN: INPDAR</identifier><language>eng</language><publisher>New Delhi: Indian Pediatrics</publisher><subject>Antitubercular Agents - therapeutic use ; Bacterial diseases ; Biological and medical sciences ; Child ; Child, Preschool ; Fractional Precipitation ; Human bacterial diseases ; Humans ; Infant ; Infectious diseases ; Medical sciences ; Tropical medicine ; Tuberculosis and atypical mycobacterial infections ; Tuberculosis, Meningeal - cerebrospinal fluid ; Tuberculosis, Meningeal - drug therapy</subject><ispartof>Indian pediatrics, 1994-03, Vol.31 (3), p.301-304</ispartof><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4242797$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7896365$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>VEENA GUPTA</creatorcontrib><creatorcontrib>AGARWAL, V. K</creatorcontrib><creatorcontrib>MATHUR, S</creatorcontrib><creatorcontrib>TRIPATHI, V. N</creatorcontrib><creatorcontrib>ASHA AGARWAL</creatorcontrib><creatorcontrib>MAYA BHALLA</creatorcontrib><creatorcontrib>KHADWEL, A</creatorcontrib><title>Modified Levinson's test in rapid diagnosis of tuberculous meningitis</title><title>Indian pediatrics</title><addtitle>Indian Pediatr</addtitle><description>Modified Levinson's precipitation test was done in 64 cases of TBM, 54 cases of TBM with inconsistent CSF finding, and 32 cases of pyogenic meningitis. The test was positive in 93.7% cases of TBM (sensitivity, 93.7%), 85.5% cases of TBM with doubtful diagnosis and in 9.4% cases of pyogenic meningitis (specificity 90.6%) compared to 79.7%, 72.2% and 18.8% in original Levinson's test, respectively. With CSF examination only 66% cases of TBM could be diagnosed while with modified Levinson's test and CSF analysis 89% cases could be diagnosed (p < 0.001). So modified Levinson's test for diagnosis of TBM is better than Levinson's test (p < 0.05) with an added advantage of time saving.</description><subject>Antitubercular Agents - therapeutic use</subject><subject>Bacterial diseases</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Fractional Precipitation</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infant</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Tropical medicine</subject><subject>Tuberculosis and atypical mycobacterial infections</subject><subject>Tuberculosis, Meningeal - cerebrospinal fluid</subject><subject>Tuberculosis, Meningeal - drug therapy</subject><issn>0019-6061</issn><issn>0974-7559</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9j8tKxEAQRRtRxnH0E4ReiK4C_X4sZRgfEHEz-1Dp7gwtSSemE8G_N2KwNlVwD8W5Z2hLrBaFltKeLzehtlBE0Ut0lfMHIYwzSTdoo41VXMktOrz1PjYxeFyGr5hynx4ynkKecEx4hCF67COcUp9jxn2Dp7kOo5vbfs64CymmU5xivkYXDbQ53Kx7h45Ph-P-pSjfn1_3j2UxUEmmItQShFDeCmkYY4I1HJzyELiuBTWOe_CeaUaNUQIaza1jVJlgnTDOW75D939vh7H_nBfJqovZhbaFFBahSv8O42QBb1dwrrvgq2GMHYzf1Vp7ye_WHLKDthkhuZj_MbGoaav5D9NcYXY</recordid><startdate>199403</startdate><enddate>199403</enddate><creator>VEENA GUPTA</creator><creator>AGARWAL, V. K</creator><creator>MATHUR, S</creator><creator>TRIPATHI, V. N</creator><creator>ASHA AGARWAL</creator><creator>MAYA BHALLA</creator><creator>KHADWEL, A</creator><general>Indian Pediatrics</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199403</creationdate><title>Modified Levinson's test in rapid diagnosis of tuberculous meningitis</title><author>VEENA GUPTA ; AGARWAL, V. K ; MATHUR, S ; TRIPATHI, V. N ; ASHA AGARWAL ; MAYA BHALLA ; KHADWEL, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p150t-eb5a446d945822242f3ac6dae37b418c3dadd27218864af739c2168e9c48cd93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Antitubercular Agents - therapeutic use</topic><topic>Bacterial diseases</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Fractional Precipitation</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infant</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Tropical medicine</topic><topic>Tuberculosis and atypical mycobacterial infections</topic><topic>Tuberculosis, Meningeal - cerebrospinal fluid</topic><topic>Tuberculosis, Meningeal - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>VEENA GUPTA</creatorcontrib><creatorcontrib>AGARWAL, V. K</creatorcontrib><creatorcontrib>MATHUR, S</creatorcontrib><creatorcontrib>TRIPATHI, V. N</creatorcontrib><creatorcontrib>ASHA AGARWAL</creatorcontrib><creatorcontrib>MAYA BHALLA</creatorcontrib><creatorcontrib>KHADWEL, A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Indian pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>VEENA GUPTA</au><au>AGARWAL, V. K</au><au>MATHUR, S</au><au>TRIPATHI, V. N</au><au>ASHA AGARWAL</au><au>MAYA BHALLA</au><au>KHADWEL, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Modified Levinson's test in rapid diagnosis of tuberculous meningitis</atitle><jtitle>Indian pediatrics</jtitle><addtitle>Indian Pediatr</addtitle><date>1994-03</date><risdate>1994</risdate><volume>31</volume><issue>3</issue><spage>301</spage><epage>304</epage><pages>301-304</pages><issn>0019-6061</issn><eissn>0974-7559</eissn><coden>INPDAR</coden><abstract>Modified Levinson's precipitation test was done in 64 cases of TBM, 54 cases of TBM with inconsistent CSF finding, and 32 cases of pyogenic meningitis. The test was positive in 93.7% cases of TBM (sensitivity, 93.7%), 85.5% cases of TBM with doubtful diagnosis and in 9.4% cases of pyogenic meningitis (specificity 90.6%) compared to 79.7%, 72.2% and 18.8% in original Levinson's test, respectively. With CSF examination only 66% cases of TBM could be diagnosed while with modified Levinson's test and CSF analysis 89% cases could be diagnosed (p < 0.001). So modified Levinson's test for diagnosis of TBM is better than Levinson's test (p < 0.05) with an added advantage of time saving.</abstract><cop>New Delhi</cop><pub>Indian Pediatrics</pub><pmid>7896365</pmid><tpages>4</tpages></addata></record> |
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subjects | Antitubercular Agents - therapeutic use Bacterial diseases Biological and medical sciences Child Child, Preschool Fractional Precipitation Human bacterial diseases Humans Infant Infectious diseases Medical sciences Tropical medicine Tuberculosis and atypical mycobacterial infections Tuberculosis, Meningeal - cerebrospinal fluid Tuberculosis, Meningeal - drug therapy |
title | Modified Levinson's test in rapid diagnosis of tuberculous meningitis |
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