Effect of polymorphism of sporozoite antigens on T-cell activation

One of the most studied candidate antigens for vaccines directed against the sporozoite stage of the malaria life-cycle is the circumsporozoite (CS) protein. This is a protein covering the surface of the sporozoite whose apparent function is to mediate binding to the sporozoite to a hepatocyte ligan...

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Veröffentlicht in:	Research in immunology (Paris) 1994-01, Vol.145 (6), p.469-476
Hauptverfasser:	Zevering, Y., Khamboonruang, C., Good, M.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Amino Acid Sequence Animals Antigens, Protozoan - immunology Apicomplexa - immunology CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Epitopes - immunology Humans Lymphocyte Activation - immunology Malaria, Falciparum - immunology Molecular Sequence Data Plasmodium falciparum Plasmodium falciparum - immunology Polymorphism, Genetic Protozoan Proteins - genetics Protozoan Proteins - immunology
Online-Zugang:	Volltext
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