Effects of Various Isoquinoline Alkaloids on In Vitro 3H-Dopamine Uptake by Rat Striatal Synaptosomes

Various alkaloids having an isoquinoline skeleton from different species of the Annonaceae, Fumariacae, and Aristolochiacae (aporphine, cularine, benzylisoquinoline, and bisbenzylisoquinoline derivatives) were tested for their ability to inhibit in vitro 3H-dopamine uptake by rat striatal dopamine D...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1995-10, Vol.58 (10), p.1475-1484
Hauptverfasser:	Protais, Philippe, Arbaoui, Jeannette, Bakkali, El-Hassan, Bermejo, Almudena, Cortes, Diego
Format:	Artikel
Sprache:	eng
Schlagworte:	ALCALOIDE QUINOLIQUE ALCALOIDES DE LA QUINOLINA Alkaloids - metabolism Animals ANNONACEAE ARISTOLOCHIACEAE BARK Benzazepines - metabolism BINDING SITE Binding, Competitive BIOASSAYS Biological and medical sciences CHEMICAL COMPOSITION COMPOSICION QUIMICA COMPOSITION CHIMIQUE Corpus Striatum - metabolism CORTEZA DERIVATIVES DOPAMINA DOPAMINE Dopamine - metabolism Dopamine Antagonists - metabolism DOSAGE BIOLOGIQUE DRUG PLANTS ECORCE ENSAYO BIOLOGICO FEUILLE FUMARIACEAE General pharmacology HOJAS In Vitro Techniques INHIBICION INHIBITION LEAVES Male Medical sciences MOLECULAR CONFORMATION Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments PLANTAS MEDICINALES PLANTE MEDICINALE QUINOLINE ALKALOIDS Raclopride RAT RATA RATS Rats, Wistar Salicylamides - metabolism Synaptosomes - metabolism Tritium
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