Comparison of intrapleural versus intravenous morphine for postthoracotomy pain management
To compare the analgesic effects of intrapleural and intravenous morphine administration for postthoracotomy pain management. Randomized, prospective trial. University teaching hospital. Twenty-eight consenting patients scheduled for elective thoracotomy operations. Patients were randomly allocated...
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| Veröffentlicht in: | Journal of cardiothoracic and vascular anesthesia 1995-10, Vol.9 (5), p.538-540 |
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| container_title | Journal of cardiothoracic and vascular anesthesia |
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| creator | Aykaç, Bora Erolçay, Hülya Dikmen, Yalim Öz, Hüseyin Yillar, Okan |
| description | To compare the analgesic effects of intrapleural and intravenous morphine administration for postthoracotomy pain management.
Randomized, prospective trial.
University teaching hospital.
Twenty-eight consenting patients scheduled for elective thoracotomy operations.
Patients were randomly allocated into two groups to receive either 20 mg of intrapleural morphine (IPM group) or 20 mg of intravenous morphine (IVM group) at the end of the operation. Plasma morphine levels, arterial pressures, heart rate, verbal analog scale (VAS), respiratory rate, and PaCO
2 levels were compared in two groups.
Plasma morphine levels were significantly higher in the IVM group at the 5th minute until the 2nd postoperative hour. VAS was significantly higher in the IVM group. Respiratory rates were significantly higher in the IPM group, whereas PaCO
2 remained significantly lower than in the IVM group.
IPM achieved better analgesia than IVM and this effect is probably attributable to peripheral effects of morphine. |
| doi_str_mv | 10.1016/S1053-0770(05)80137-5 |
| format | Article |
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Randomized, prospective trial.
University teaching hospital.
Twenty-eight consenting patients scheduled for elective thoracotomy operations.
Patients were randomly allocated into two groups to receive either 20 mg of intrapleural morphine (IPM group) or 20 mg of intravenous morphine (IVM group) at the end of the operation. Plasma morphine levels, arterial pressures, heart rate, verbal analog scale (VAS), respiratory rate, and PaCO
2 levels were compared in two groups.
Plasma morphine levels were significantly higher in the IVM group at the 5th minute until the 2nd postoperative hour. VAS was significantly higher in the IVM group. Respiratory rates were significantly higher in the IPM group, whereas PaCO
2 remained significantly lower than in the IVM group.
IPM achieved better analgesia than IVM and this effect is probably attributable to peripheral effects of morphine.</description><identifier>ISSN: 1053-0770</identifier><identifier>EISSN: 1532-8422</identifier><identifier>DOI: 10.1016/S1053-0770(05)80137-5</identifier><identifier>PMID: 8547555</identifier><language>eng</language><publisher>Philadelphia, PA: Elsevier Inc</publisher><subject>Analgesia - methods ; Analgesics ; Analgesics, Opioid - administration & dosage ; Biological and medical sciences ; Female ; Humans ; Infusions, Intravenous ; intrapleural analgesia ; Male ; Medical sciences ; Middle Aged ; morphine ; Morphine - administration & dosage ; Neuropharmacology ; pain management ; Pain, Postoperative - drug therapy ; Pharmacology. Drug treatments ; Pleura ; Prospective Studies ; Thoracotomy</subject><ispartof>Journal of cardiothoracic and vascular anesthesia, 1995-10, Vol.9 (5), p.538-540</ispartof><rights>1995 W.B. Saunders Company</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-ebd92933ef3a4be70590b3493aea06016f30d0b09c9fbb385faf5efce2df513b3</citedby><cites>FETCH-LOGICAL-c414t-ebd92933ef3a4be70590b3493aea06016f30d0b09c9fbb385faf5efce2df513b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1053077005801375$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2893047$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8547555$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aykaç, Bora</creatorcontrib><creatorcontrib>Erolçay, Hülya</creatorcontrib><creatorcontrib>Dikmen, Yalim</creatorcontrib><creatorcontrib>Öz, Hüseyin</creatorcontrib><creatorcontrib>Yillar, Okan</creatorcontrib><title>Comparison of intrapleural versus intravenous morphine for postthoracotomy pain management</title><title>Journal of cardiothoracic and vascular anesthesia</title><addtitle>J Cardiothorac Vasc Anesth</addtitle><description>To compare the analgesic effects of intrapleural and intravenous morphine administration for postthoracotomy pain management.
Randomized, prospective trial.
University teaching hospital.
Twenty-eight consenting patients scheduled for elective thoracotomy operations.
Patients were randomly allocated into two groups to receive either 20 mg of intrapleural morphine (IPM group) or 20 mg of intravenous morphine (IVM group) at the end of the operation. Plasma morphine levels, arterial pressures, heart rate, verbal analog scale (VAS), respiratory rate, and PaCO
2 levels were compared in two groups.
Plasma morphine levels were significantly higher in the IVM group at the 5th minute until the 2nd postoperative hour. VAS was significantly higher in the IVM group. Respiratory rates were significantly higher in the IPM group, whereas PaCO
2 remained significantly lower than in the IVM group.
IPM achieved better analgesia than IVM and this effect is probably attributable to peripheral effects of morphine.</description><subject>Analgesia - methods</subject><subject>Analgesics</subject><subject>Analgesics, Opioid - administration & dosage</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Humans</subject><subject>Infusions, Intravenous</subject><subject>intrapleural analgesia</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>morphine</subject><subject>Morphine - administration & dosage</subject><subject>Neuropharmacology</subject><subject>pain management</subject><subject>Pain, Postoperative - drug therapy</subject><subject>Pharmacology. Drug treatments</subject><subject>Pleura</subject><subject>Prospective Studies</subject><subject>Thoracotomy</subject><issn>1053-0770</issn><issn>1532-8422</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1v1DAQQK0KVNrSn1ApB4TaQ2AcZzbJCVWrfiBV4gBcuFgTZ0yNEjvY2ZX67_F2t73ii0czb-yZJ8SFhE8S5OrzdwmoSmgauAS8akGqpsQjcSJRVWVbV9WbHL8g78RpSn8ApERsjsVxi3WDiCfi1zpMM0WXgi-CLZxfIs0jbyKNxZZj2qR9bss-5HgKcX50ngsbYjGHtCyPIZIJS5ieipmcLyby9Jsn9st78dbSmPj8cJ-Jn7c3P9b35cO3u6_r64fS1LJeSu6HruqUYquo7rkB7KBXdaeICVZ5U6tggB4609m-Vy1assjWcDVYlKpXZ-Lj_t05hr8bToueXDI8juQ5z6ybfFS7wgziHjQxpBTZ6jm6ieKTlqB3TvWzU70TpgH1s1O967s4fLDpJx5euw4Sc_3DoU7J0GgjeePSK1a1nYK6ydiXPcZZxtZx1Mk49oYHF9ksegjuP4P8AwpFleQ</recordid><startdate>19951001</startdate><enddate>19951001</enddate><creator>Aykaç, Bora</creator><creator>Erolçay, Hülya</creator><creator>Dikmen, Yalim</creator><creator>Öz, Hüseyin</creator><creator>Yillar, Okan</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19951001</creationdate><title>Comparison of intrapleural versus intravenous morphine for postthoracotomy pain management</title><author>Aykaç, Bora ; Erolçay, Hülya ; Dikmen, Yalim ; Öz, Hüseyin ; Yillar, Okan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-ebd92933ef3a4be70590b3493aea06016f30d0b09c9fbb385faf5efce2df513b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Analgesia - methods</topic><topic>Analgesics</topic><topic>Analgesics, Opioid - administration & dosage</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Humans</topic><topic>Infusions, Intravenous</topic><topic>intrapleural analgesia</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>morphine</topic><topic>Morphine - administration & dosage</topic><topic>Neuropharmacology</topic><topic>pain management</topic><topic>Pain, Postoperative - drug therapy</topic><topic>Pharmacology. Drug treatments</topic><topic>Pleura</topic><topic>Prospective Studies</topic><topic>Thoracotomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aykaç, Bora</creatorcontrib><creatorcontrib>Erolçay, Hülya</creatorcontrib><creatorcontrib>Dikmen, Yalim</creatorcontrib><creatorcontrib>Öz, Hüseyin</creatorcontrib><creatorcontrib>Yillar, Okan</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cardiothoracic and vascular anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aykaç, Bora</au><au>Erolçay, Hülya</au><au>Dikmen, Yalim</au><au>Öz, Hüseyin</au><au>Yillar, Okan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of intrapleural versus intravenous morphine for postthoracotomy pain management</atitle><jtitle>Journal of cardiothoracic and vascular anesthesia</jtitle><addtitle>J Cardiothorac Vasc Anesth</addtitle><date>1995-10-01</date><risdate>1995</risdate><volume>9</volume><issue>5</issue><spage>538</spage><epage>540</epage><pages>538-540</pages><issn>1053-0770</issn><eissn>1532-8422</eissn><abstract>To compare the analgesic effects of intrapleural and intravenous morphine administration for postthoracotomy pain management.
Randomized, prospective trial.
University teaching hospital.
Twenty-eight consenting patients scheduled for elective thoracotomy operations.
Patients were randomly allocated into two groups to receive either 20 mg of intrapleural morphine (IPM group) or 20 mg of intravenous morphine (IVM group) at the end of the operation. Plasma morphine levels, arterial pressures, heart rate, verbal analog scale (VAS), respiratory rate, and PaCO
2 levels were compared in two groups.
Plasma morphine levels were significantly higher in the IVM group at the 5th minute until the 2nd postoperative hour. VAS was significantly higher in the IVM group. Respiratory rates were significantly higher in the IPM group, whereas PaCO
2 remained significantly lower than in the IVM group.
IPM achieved better analgesia than IVM and this effect is probably attributable to peripheral effects of morphine.</abstract><cop>Philadelphia, PA</cop><pub>Elsevier Inc</pub><pmid>8547555</pmid><doi>10.1016/S1053-0770(05)80137-5</doi><tpages>3</tpages></addata></record> |
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| identifier | ISSN: 1053-0770 |
| ispartof | Journal of cardiothoracic and vascular anesthesia, 1995-10, Vol.9 (5), p.538-540 |
| issn | 1053-0770 1532-8422 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Analgesia - methods Analgesics Analgesics, Opioid - administration & dosage Biological and medical sciences Female Humans Infusions, Intravenous intrapleural analgesia Male Medical sciences Middle Aged morphine Morphine - administration & dosage Neuropharmacology pain management Pain, Postoperative - drug therapy Pharmacology. Drug treatments Pleura Prospective Studies Thoracotomy |
| title | Comparison of intrapleural versus intravenous morphine for postthoracotomy pain management |
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