Stability of Recombinant Consensus Interferon to Air‐Jet and Ultrasonic Nebulization

The stability of recombinant consensus α‐interferon (rConIFN) to air‐jet and ultrasonic nebulization was evaluated. Volumes of 10 mL of 0.5mg/mL rConIFN in phosphate‐buffered saline (PBS) at pH 6.3 were nebulized with a Collison three‐jet nebulizer at 40 psig (10 L/min) for up to 25 min. The effects...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of pharmaceutical sciences 1995-10, Vol.84 (10), p.1210-1214
Hauptverfasser:	Ip, Anna Y., Arakawa, Tsutomu, Silvers, Helen, Ransone, Charles M., Niven, Ralph W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Biological and medical sciences Chemical Phenomena Chemistry, Physical Consensus Sequence Drug Stability Immunomodulators Interferon Type I - administration & dosage Interferon Type I - chemistry Medical sciences Nebulizers and Vaporizers Pharmacology. Drug treatments Recombinant Proteins Solutions
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!