Designing a cost-effective clinical trial

Researchers and administrators must decide which clinical trials are worth doing and how many subjects are needed for a trial. We calculated sample size considering the costs of implementing the results of the trial and the trial costs using (1) Neyman—Pearson methods and (2) a Bayesian cost—benefit...

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Veröffentlicht in:Statistics in medicine 1995-10, Vol.14 (20), p.2249-2259
Hauptverfasser: Hornberger, John C., Brown Jr, Byron Wm, Halpern, Jerry
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Sprache:eng
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