Hypotonically activated chloride current in HSG cells

Hypotonically induced changes in whole-cell currents and in cell volume were studied in the HSG cloned cell line using the whole-cell, patch clamp and Coulter counter techniques, respectively. Exposures to 10 to 50% hypotonic solutions induced dose-dependent increases in whole-cell conductances when...

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Veröffentlicht in:	The Journal of membrane biology 1994-11, Vol.142 (2), p.181-193
Hauptverfasser:	Fatherazi, S, Izutsu, K T, Wellner, R B, Belton, C M
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid - pharmacology Actins - physiology Arachidonic Acid - pharmacology Calcium - metabolism Cell Line Cell Membrane - drug effects Cell Membrane - physiology Cell Membrane - ultrastructure Chloride Channels - antagonists & inhibitors Chloride Channels - drug effects Chloride Channels - physiology Cytochalasin D - pharmacology Cytoskeleton - physiology Dose-Response Relationship, Drug Egtazic Acid - analogs & derivatives Egtazic Acid - pharmacology Guanosine Triphosphate - pharmacology Humans Hypotonic Solutions - pharmacology Nitrobenzoates - pharmacology Patch-Clamp Techniques Potassium Channels - physiology Quinacrine - pharmacology Submandibular Gland - cytology Submandibular Gland - physiology Submandibular Gland - ultrastructure
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