An amyloid β-protein fragment, Aβ[12–28], equipotently impairs post-training memory processing when injected into different limbic system structures

Previously, amyloid β-protein (Aβ) fragments 1–28, 12–28 and 12–20 were found to impair retention in mice when injected intracerebroventricularly after footschock active avoidance training. We now have measured the dose-dependence of amnestic effects of peptide 12–28 stereotacally injected into amyg...

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