Hereditary and Acquired Risk Factors for Childhood Stroke
Abstract Forty-four patients aged from one month to 16 years suffering from arterial stroke were carefully studied for any hereditary and acquired risk factors for stroke. No physiologic anticoagulant deficiency or antiphospholipid syndrome was found. Two patients had mitochondrial diseases (MELAS)....
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Veröffentlicht in: | Neuropediatrics 1994-10, Vol.25 (5), p.227-233 |
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description | Abstract
Forty-four patients aged from one month to 16 years suffering from arterial stroke were carefully studied for any hereditary and acquired risk factors for stroke. No physiologic anticoagulant deficiency or antiphospholipid syndrome was found. Two patients had mitochondrial diseases (MELAS). Six patients had migraineous stroke. Migraine and thrombotic disease in the families of the patients were not more prevalent than in the families of the controls. Preceding infections occurred in 34% of the patients, that is, significantly more common than in the age-matched controls. Two children had borreliosis. Repeat strokes occurred particularly in patients with migraine (n = 4) and MELAS (n = 2).
The hereditary factors studied here seem to play only a minor role in pediatric patients. Repeated strokes have a varied etiology and are difficult to prevent. Important triggers of strokes are infections. |
doi_str_mv | 10.1055/s-2008-1073026 |
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Forty-four patients aged from one month to 16 years suffering from arterial stroke were carefully studied for any hereditary and acquired risk factors for stroke. No physiologic anticoagulant deficiency or antiphospholipid syndrome was found. Two patients had mitochondrial diseases (MELAS). Six patients had migraineous stroke. Migraine and thrombotic disease in the families of the patients were not more prevalent than in the families of the controls. Preceding infections occurred in 34% of the patients, that is, significantly more common than in the age-matched controls. Two children had borreliosis. Repeat strokes occurred particularly in patients with migraine (n = 4) and MELAS (n = 2).
The hereditary factors studied here seem to play only a minor role in pediatric patients. Repeated strokes have a varied etiology and are difficult to prevent. Important triggers of strokes are infections.</description><identifier>ISSN: 0174-304X</identifier><identifier>EISSN: 1439-1899</identifier><identifier>DOI: 10.1055/s-2008-1073026</identifier><identifier>PMID: 7885530</identifier><identifier>CODEN: NRPDDB</identifier><language>eng</language><publisher>Stuttgart: Thieme</publisher><subject>Adolescent ; Biological and medical sciences ; Case-Control Studies ; Cerebrovascular Disorders - epidemiology ; Cerebrovascular Disorders - etiology ; Cerebrovascular Disorders - genetics ; Chi-Square Distribution ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Infection - complications ; Male ; Medical sciences ; MELAS Syndrome - complications ; Migraine Disorders - complications ; Neurology ; Original article ; Recurrence ; Risk Factors ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>Neuropediatrics, 1994-10, Vol.25 (5), p.227-233</ispartof><rights>Georg Thieme Verlag KG Stuttgart · New York</rights><rights>1995 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c452t-1d88289fcb0008644c17f8ce2cd2b4e6fb5e7b1784ac57a2e110f3db327d99243</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2008-1073026.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><link.rule.ids>314,776,780,3004,3005,27901,27902,54534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3387000$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7885530$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Riikonen, R.</creatorcontrib><creatorcontrib>Santavuori, P.</creatorcontrib><title>Hereditary and Acquired Risk Factors for Childhood Stroke</title><title>Neuropediatrics</title><addtitle>Neuropediatrics</addtitle><description>Abstract
Forty-four patients aged from one month to 16 years suffering from arterial stroke were carefully studied for any hereditary and acquired risk factors for stroke. No physiologic anticoagulant deficiency or antiphospholipid syndrome was found. Two patients had mitochondrial diseases (MELAS). Six patients had migraineous stroke. Migraine and thrombotic disease in the families of the patients were not more prevalent than in the families of the controls. Preceding infections occurred in 34% of the patients, that is, significantly more common than in the age-matched controls. Two children had borreliosis. Repeat strokes occurred particularly in patients with migraine (n = 4) and MELAS (n = 2).
The hereditary factors studied here seem to play only a minor role in pediatric patients. Repeated strokes have a varied etiology and are difficult to prevent. Important triggers of strokes are infections.</description><subject>Adolescent</subject><subject>Biological and medical sciences</subject><subject>Case-Control Studies</subject><subject>Cerebrovascular Disorders - epidemiology</subject><subject>Cerebrovascular Disorders - etiology</subject><subject>Cerebrovascular Disorders - genetics</subject><subject>Chi-Square Distribution</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infection - complications</subject><subject>Male</subject><subject>Medical sciences</subject><subject>MELAS Syndrome - complications</subject><subject>Migraine Disorders - complications</subject><subject>Neurology</subject><subject>Original article</subject><subject>Recurrence</subject><subject>Risk Factors</subject><subject>Vascular diseases and vascular malformations of the nervous system</subject><issn>0174-304X</issn><issn>1439-1899</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kElLAzEUgIMotVav3oQ5iLep2WaSHEuxVigILuAtZLLQaWeaNpk5-O9N6dCbpwfvfW_7ALhHcIpgUTzHHEPIcwQZgbi8AGNEicgRF-ISjCFiNCeQ_lyDmxg3ECIqYDkCI8Z5URA4BmJpgzV1p8JvpnYmm-lDX6dM9lHHbbZQuvMhZs6HbL6uG7P23mSfXfBbewuunGqivRviBHwvXr7my3z1_vo2n61yTQvc5chwjrlwuoLpzpJSjZjj2mJtcEVt6arCsgoxTpUumMIWIeiIqQhmRghMyQQ8nebugz_0NnayraO2TaN21vdRMsZKKjhK4PQE6uBjDNbJfajb9JhEUB5dySiPruTgKjU8DJP7qrXmjA9yUv1xqKuoVeOC2uk6njFCOEs_JSw_Yd26tq2VG9-HXTLy39o_oOR9nQ</recordid><startdate>19941001</startdate><enddate>19941001</enddate><creator>Riikonen, R.</creator><creator>Santavuori, P.</creator><general>Thieme</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19941001</creationdate><title>Hereditary and Acquired Risk Factors for Childhood Stroke</title><author>Riikonen, R. ; Santavuori, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c452t-1d88289fcb0008644c17f8ce2cd2b4e6fb5e7b1784ac57a2e110f3db327d99243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adolescent</topic><topic>Biological and medical sciences</topic><topic>Case-Control Studies</topic><topic>Cerebrovascular Disorders - epidemiology</topic><topic>Cerebrovascular Disorders - etiology</topic><topic>Cerebrovascular Disorders - genetics</topic><topic>Chi-Square Distribution</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Infection - complications</topic><topic>Male</topic><topic>Medical sciences</topic><topic>MELAS Syndrome - complications</topic><topic>Migraine Disorders - complications</topic><topic>Neurology</topic><topic>Original article</topic><topic>Recurrence</topic><topic>Risk Factors</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Riikonen, R.</creatorcontrib><creatorcontrib>Santavuori, P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuropediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Riikonen, R.</au><au>Santavuori, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hereditary and Acquired Risk Factors for Childhood Stroke</atitle><jtitle>Neuropediatrics</jtitle><addtitle>Neuropediatrics</addtitle><date>1994-10-01</date><risdate>1994</risdate><volume>25</volume><issue>5</issue><spage>227</spage><epage>233</epage><pages>227-233</pages><issn>0174-304X</issn><eissn>1439-1899</eissn><coden>NRPDDB</coden><abstract>Abstract
Forty-four patients aged from one month to 16 years suffering from arterial stroke were carefully studied for any hereditary and acquired risk factors for stroke. No physiologic anticoagulant deficiency or antiphospholipid syndrome was found. Two patients had mitochondrial diseases (MELAS). Six patients had migraineous stroke. Migraine and thrombotic disease in the families of the patients were not more prevalent than in the families of the controls. Preceding infections occurred in 34% of the patients, that is, significantly more common than in the age-matched controls. Two children had borreliosis. Repeat strokes occurred particularly in patients with migraine (n = 4) and MELAS (n = 2).
The hereditary factors studied here seem to play only a minor role in pediatric patients. Repeated strokes have a varied etiology and are difficult to prevent. Important triggers of strokes are infections.</abstract><cop>Stuttgart</cop><pub>Thieme</pub><pmid>7885530</pmid><doi>10.1055/s-2008-1073026</doi><tpages>7</tpages></addata></record> |
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subjects | Adolescent Biological and medical sciences Case-Control Studies Cerebrovascular Disorders - epidemiology Cerebrovascular Disorders - etiology Cerebrovascular Disorders - genetics Chi-Square Distribution Child Child, Preschool Female Humans Infant Infection - complications Male Medical sciences MELAS Syndrome - complications Migraine Disorders - complications Neurology Original article Recurrence Risk Factors Vascular diseases and vascular malformations of the nervous system |
title | Hereditary and Acquired Risk Factors for Childhood Stroke |
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