High Yield, Site-Specific Coupling of N-Terminally Modified .beta.-Lactamase to a Proteolytically Derived Single-Sulfhydryl Murine Fab

The preparation of bispecific protein conjugates capable of performing diverse biological functions is an area of active investigation. Such conjugates are routinely prepared using techniques which employ random derivatization of lysine residues, but the overall utility of these methods is limited d...

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Veröffentlicht in:Bioconjugate chemistry 1994-11, Vol.5 (6), p.636-646
Hauptverfasser: Mikolajczyk, Stephen D, Meyer, Damon L, Starling, James J, Law, Kevin L, Rose, Keith, Dufour, Brigitte, Offord, Robin E
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Sprache:eng
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