Medicinal chemistry of muscarinic agonists for the treatment of dementia disorders

Alzheimer disease (AD) is a neurodegenerative disorder lacking an effective therapy. The etiology is controversial and among different drug strategies, the cholinergic approach has gained great interest owing to biochemical and pharmacological evidence of the crucial role of acetylcholine in cogniti...

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Veröffentlicht in:	European journal of drug metabolism and pharmacokinetics 1994-07, Vol.19 (3), p.179-183
Hauptverfasser:	CEREDA, E, BRAMBILLA, A, EZHAYA, A, GAIDA, W, MENDLA, K, MONFERINI, E, PITSIKAS, N, SCHIAVI, G. B, SAGRADA, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Animals Biological and medical sciences Brain - drug effects CHO Cells Cholinergic system Cricetinae Female Learning - drug effects Male Medical sciences Muscarinic Agonists - metabolism Muscarinic Agonists - pharmacology Muscarinic Agonists - therapeutic use Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pharmacology. Drug treatments Rabbits Rats Receptors, Muscarinic - metabolism
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