Upregulation of Nerve Growth Factor Following Cortical Trauma

As part of the inflammatory response to brain injury, CSF and tissue levels of interleukin-1β (IL-1β) are elevated after trauma. This elevation in IL-1β initiates a cascade of events among which may be an upregulation in nerve growth factor (NGF) in brain tissue. We infused IL-1β into the ventricle...

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Veröffentlicht in:	Experimental neurology 1994-12, Vol.130 (2), p.173-177
Hauptverfasser:	DeKosky, Steven T., Goss, James R., Miller, Peter D., Styren, Scot D., Kochanek, Patrick M., Marion, Donald
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blotting, Northern Brain Concussion - metabolism Cerebral Cortex - injuries Enzyme-Linked Immunosorbent Assay Injections, Intraventricular Injuries of the nervous system and the skull. Diseases due to physical agents Interleukin-1 - pharmacology Male Medical sciences Nerve Growth Factors - genetics Nerve Growth Factors - metabolism Rats Rats, Inbred F344 Rats, Wistar RNA, Messenger - metabolism Traumas. Diseases due to physical agents Wounds, Nonpenetrating - metabolism
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