Acute vs. chronic EEG effects in maprotiline- and in clomipramine-treated depressive inpatients and the prediction of therapeutic outcome

Patients treated with the norepinephrine uptake inhibitor maprotiline showed an opposite tendency between acute and chronic effect of EEG. Whereas the acute effect indicated a decrease upon EEG vigilance, the chronic effect indicated an increase. Under clomipramine which acts upon different transmit...

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Veröffentlicht in:Journal of affective disorders 1994-11, Vol.32 (3), p.213-217
Hauptverfasser: Ulrich, G., Haug, H.-J., Fähndrich, E.
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container_title Journal of affective disorders
container_volume 32
creator Ulrich, G.
Haug, H.-J.
Fähndrich, E.
description Patients treated with the norepinephrine uptake inhibitor maprotiline showed an opposite tendency between acute and chronic effect of EEG. Whereas the acute effect indicated a decrease upon EEG vigilance, the chronic effect indicated an increase. Under clomipramine which acts upon different transmitter systems in a complex, up to now not fully understood way, acute and chronic EEG effects could not be differentiated.
doi_str_mv 10.1016/0165-0327(94)90020-5
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Psychiatry</topic><topic>Psychopharmacology</topic><topic>Test-dose model</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ulrich, G.</creatorcontrib><creatorcontrib>Haug, H.-J.</creatorcontrib><creatorcontrib>Fähndrich, E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of affective disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ulrich, G.</au><au>Haug, H.-J.</au><au>Fähndrich, E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute vs. chronic EEG effects in maprotiline- and in clomipramine-treated depressive inpatients and the prediction of therapeutic outcome</atitle><jtitle>Journal of affective disorders</jtitle><addtitle>J Affect Disord</addtitle><date>1994-11</date><risdate>1994</risdate><volume>32</volume><issue>3</issue><spage>213</spage><epage>217</epage><pages>213-217</pages><issn>0165-0327</issn><eissn>1573-2517</eissn><coden>JADID7</coden><abstract>Patients treated with the norepinephrine uptake inhibitor maprotiline showed an opposite tendency between acute and chronic effect of EEG. 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subjects Acute vs. chronic effects
Adult
Aged
Antidepressive drug
Biological and medical sciences
Clomipramine - administration & dosage
Clomipramine - pharmacology
Clomipramine - therapeutic use
Depressive Disorder - diagnosis
Depressive Disorder - drug therapy
Dose-Response Relationship, Drug
EEG vigilance
Electroencephalography - drug effects
Female
Humans
Male
Maprotiline - administration & dosage
Maprotiline - pharmacology
Maprotiline - therapeutic use
Medical sciences
Middle Aged
Neuropharmacology
Pharmacology. Drug treatments
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Test-dose model
Treatment Outcome
title Acute vs. chronic EEG effects in maprotiline- and in clomipramine-treated depressive inpatients and the prediction of therapeutic outcome
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