Neutrophil inhibitory factor is neuroprotective after focal Ischemia in rats

We tested the neuroprotective potential of neutrophil inhibitory factor (rNIF), a novel 41‐kd recombinant glycoprotein derived from a hookworm, in a model of focal cerebral ischemia in the rat. Male Wistar rats were assigned to treatment with rNIF and vehicle. Middle cerebral artery occlusion (MCAO)...

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Veröffentlicht in:	Annals of neurology 1995-12, Vol.38 (6), p.935-942
Hauptverfasser:	Jiang, Ning, Moyle, Matthew, Soule, Howard R., Rote, William E., Chopp, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Gas Analysis Body Weight Brain Ischemia - drug therapy Glycoproteins - blood Glycoproteins - pharmacology Helminth Proteins - blood Helminth Proteins - pharmacology Infusions, Intravenous Leukocyte Count Male Medical sciences Membrane Proteins Neuropharmacology Neuroprotective agent Neuroprotective Agents - pharmacology Neutrophils - cytology Pharmacology. Drug treatments Rats Rats, Wistar Recombinant Proteins - pharmacology Reperfusion Injury - drug therapy Reperfusion Injury - immunology Temperature
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