Operant response suppression induced with systemic administration of 5-hydroxytryptophan is centrally mediated

Intracerebroventricular (ICV) administration of selective serotonergic agents was used to examine the extent of central mediation of 5-HTP-induced operant response suppression in rats. ICV administration of LY53857 (1.0, 3.75, or 7.5 μg/5 μl/5 min) dose dependently blocked response suppression induc...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1995-11, Vol.52 (3), p.525-529
Hauptverfasser:	Engleman, Eric A., Murphy, James M., Zhou, Feng C., Aprison, Morris H., Hingtgen, Joseph N.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT 2 receptors 5-Hydroxytryptophan 5-Hydroxytryptophan - administration & dosage 5-Hydroxytryptophan - pharmacology Amphetamines - pharmacology Animal Animals Behavior Biological and medical sciences Brain - drug effects Brain - physiology Conditioning Conditioning, Operant - drug effects Depression Intracerebroventricular administration Dose-Response Relationship, Drug Ergolines - administration & dosage Ergolines - pharmacology Fundamental and applied biological sciences. Psychology Injections, Intraventricular Learning. Memory Male Microinjections Operant conditioning Operant responding Peripheral Nervous System - drug effects Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Sprague-Dawley Rats, Wistar Receptors, Serotonin - drug effects Serotonin Serotonin agonists Serotonin antagonists Serotonin Antagonists - administration & dosage Serotonin Antagonists - pharmacology Serotonin Receptor Agonists - pharmacology Stereotaxic Techniques
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