Pathogenesis of Rhodococcus equi infection in mice: Roles of virulence plasmids and granulomagenic activity of bacteria

Virulence of Rhocococcus equi ATCC 33701 and its plasmid‐cured derivative ATCC 33701P− was compared in BALB/c and C3H/HeJ mice in terms of bacterial growth kinetics and histological changes in the liver, spleen and lungs, and humoral immune responses. Injection with a sublethal dose of 106 ATCC 3370...

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Veröffentlicht in:	FEMS immunology and medical microbiology 1995-06, Vol.11 (3), p.181-190
Hauptverfasser:	Takai, Shinji, Madarame, Hiroo, Matsumoto, Chizuko, Inoue, Maki, Sasaki, Yukako, Hasegawa, Yoshihisa, Tsubaki, Shiro, Nakane, Akio
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinomycetales Infections - etiology Actinomycetales Infections - immunology Actinomycetales Infections - pathology Animals Antibodies, Bacterial - blood Female Glycolipids - physiology Granuloma - etiology Granuloma - pathology Granulomagenic activity Liver Diseases - etiology Liver Diseases - pathology Mice Mice, Inbred BALB C Mice, Inbred C3H Organ Size Pathogenesis Plasmids Rhodococcus equi Rhodococcus equi - genetics Rhodococcus equi - immunology Rhodococcus equi - pathogenicity Species Specificity Spleen - pathology Splenic Diseases - etiology Splenic Diseases - pathology Virulence - genetics Virulence plasmid
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