Metabolism of equilin sulfate in the dog

The metabolism of equilin sulfate was determined in female dogs receiving 2.5 mg/kg of [ 3H]equilin sulfate alone or in a preparation that contained all the components that are present in the conjugated equine estrogen product Premarin ®. The pharmacokinetic parameters of total radioactivity indicat...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 1995-11, Vol.55 (2), p.271-278
Hauptverfasser:	Chandrasekaran, A., Osman, M., Scatina, J.A., Sisenwine, S.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biotransformation Chromatography, High Pressure Liquid Dogs Drug Combinations Equilin - analogs & derivatives Equilin - blood Equilin - metabolism Equilin - pharmacokinetics Estrogens, Conjugated (USP) - blood Estrogens, Conjugated (USP) - metabolism Estrogens, Conjugated (USP) - pharmacokinetics Estrogens, Conjugated (USP) - pharmacology Female Gas Chromatography-Mass Spectrometry Half-Life Hormones. Endocrine system Medical sciences Metabolic Clearance Rate Pharmacology. Drug treatments Radioisotope Dilution Technique Tritium
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